Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882883 | 0.91 | USP2 (0.33) | HSD17B10HSP90AB1LMNACYP1A2USP2 | |
| SCHEMBL4882039 | 0.87 | USP2 (0.33) | HSD17B10HSP90AB1CYP1A2USP2CYP3A4 | |
| SCHEMBL4884416 | 0.82 | USP2 (0.35) | HSD17B10CYP1A2USP2CYP3A4CNR1 | |
| SCHEMBL5145778 | 0.78 | HSP90AB1 (0.48) | HSP90AB1LMNAMAPTLSS | |
| SCHEMBL4875728 | 0.77 | HSP90AB1 (0.35) | HSD17B10HSP90AB1LMNACYP1A2TRPV1 | |
| SCHEMBL4881588 | 0.74 | MAPK1 (0.33) | HSD17B10HSP90AB1LMNACYP1A2USP2 | |
| SCHEMBL5145876 | 0.72 | PDE4B (0.42) | HSP90AB1LMNAUSP2MAPTLSS | |
| SCHEMBL4887345 | 0.70 | TIPARP (0.36) | HSD17B10HSP90AB1LMNACYP1A2USP2 | |
| SCHEMBL5141466 | 0.69 | MAPT (0.53) | HSD17B10LMNACYP1A2USP2CYP3A4 | |
| SCHEMBL5141439 | 0.69 | SIGMAR1 (0.49) | LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234252-A1 | Compounds Useful in Therapy | PFIZER INC | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234252-A1 | Compounds Useful in Therapy | AVPR1A, AVPR1B, AVPR2 | HSD17B10 1110/4885HSP90AB1 2905/4885LMNA 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.