Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881580 | 0.91 | HSD17B10 (0.35) | USP2CYP1A2CYP3A4HSP90AB1HSD17B10 | |
| SCHEMBL4884416 | 0.86 | USP2 (0.35) | USP2CYP1A2CYP3A4HSD17B10CNR1 | |
| SCHEMBL4882039 | 0.82 | USP2 (0.33) | USP2CYP1A2CYP3A4HSP90AB1HSD17B10 | |
| SCHEMBL4875728 | 0.73 | HSP90AB1 (0.35) | CYP1A2HSP90AB1HSD17B10CYP2C19LMNA | |
| SCHEMBL4887345 | 0.72 | TIPARP (0.36) | USP2CYP1A2CYP3A4HSP90AB1HSD17B10 | |
| SCHEMBL4876933 | 0.71 | AVPR2 (0.33) | USP2CYP1A2CYP3A4HSP90AB1KCNH2 | |
| SCHEMBL4619490 | 0.68 | TRPA1 (0.39) | USP2CYP1A2CYP3A4HSD17B10CYP2C19 | |
| SCHEMBL4881588 | 0.68 | MAPK1 (0.33) | USP2CYP1A2CYP3A4HSP90AB1HSD17B10 | |
| SCHEMBL28758727 | 0.68 | TLR8 (0.36) | HSD17B10KCNH2AVPR2OXTRAVPR1A | |
| SCHEMBL4740390 | 0.67 | TRPA1 (0.30) | CNR1CNR2AVPR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234252-A1 | Compounds Useful in Therapy | PFIZER INC | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234252-A1 | Compounds Useful in Therapy | AVPR1A, AVPR1B, AVPR2 | USP2 4648/4885CYP1A2 552/4885CYP3A4 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.