Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16050622 | 0.86 | CDK2 (0.51) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL14280912 | 0.82 | CDK2 (0.49) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL4873071 | 0.80 | CDK2 (0.47) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL4866520 | 0.76 | CSNK2B (0.33) | — | |
| SCHEMBL4872259 | 0.76 | CDK2 (0.44) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL5438939 | 0.76 | CDK2 (0.48) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL6623749 | 0.74 | KDM5A (0.45) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL18863648 | 0.73 | CDK2 (0.45) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL6626868 | 0.72 | KDM4E (0.49) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL5771717 | 0.72 | MEN1 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981848-A2 | 11-BETA HSD1 INHIBITORS | Wyeth (US) | 2008-10-22 | — | — | EP | disclosed |
| US-20080021045-A1 | 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action | BAYER CROPSCIENCE AKTIENGESELLSCHSFT (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080021045-A1 | 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action | BAYER CROPSCIENCE AKTIENGESELLSCHSFT (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080021045-A1 | 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action | BAYER CROPSCIENCE AKTIENGESELLSCHSFT (DE) | 2008-01-24 | — | — | US | disclosed |
| WO-2007092435-A2 | 11-BETA HSD1 INHIBITORS | WYETH (US) | 2007-08-16 | — | — | WO | disclosed |
| EP-1694682-A1 | 7-AMINO-5-HALOPYRAZOLOPYRIMIDINES WITH A FUNGICIDAL ACTION | Bayer CropScience AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005056557-A1 | 7-AMINO-5-HALOPYRAZOLOPYRIMIDINES WITH A FUNGICIDAL ACTION | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021045-A1 | 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action | Q6ZSR9, CYP3A7, CYP4X1 | CDK2 1782/4885KDM5A 951/4885KDM4C 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.