Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280912 | 0.86 | CDK2 (0.49) | CDK2PDE2AKDM5AKDM4CKDM4E | |
| SCHEMBL14280908 | 0.83 | MEN1 (0.32) | CDK2KMT2A | |
| SCHEMBL4866649 | 0.81 | — | — | |
| SCHEMBL13606365 | 0.81 | GBA1 (0.40) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL4874084 | 0.80 | GBA1 (0.39) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL14280906 | 0.80 | — | — | |
| SCHEMBL4875792 | 0.80 | CDK2 (0.50) | CDK2KDM5AKDM4CKDM4EALDH1A1 | |
| SCHEMBL13606364 | 0.79 | KDM4E (0.40) | CDK2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14280903 | 0.77 | — | — | |
| SCHEMBL4869992 | 0.75 | KCNN3 (0.37) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021045-A1 | 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action | BAYER CROPSCIENCE AKTIENGESELLSCHSFT (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080021045-A1 | 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action | BAYER CROPSCIENCE AKTIENGESELLSCHSFT (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080021045-A1 | 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action | BAYER CROPSCIENCE AKTIENGESELLSCHSFT (DE) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021045-A1 | 7-Amino-5-Halopyrazolopyrimidines with a Fungicidal Action | Q6ZSR9, CYP3A7, CYP4X1 | CDK2 1782/4885PDE2A 900/4885KDM5A 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.