Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | OGG1 | O15527 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876180 | 1.00 | MTOR (0.58) | MTORCYP1A2CYP3A4CYP2C19OGG1 | |
| SCHEMBL4878014 | 0.88 | NPC1 (0.59) | MTORCYP1A2CYP3A4CYP2C19OGG1 | |
| SCHEMBL4878016 | 0.88 | NPC1 (0.59) | MTORCYP1A2CYP3A4CYP2C19OGG1 | |
| SCHEMBL4888888 | 0.87 | CYP1A2 (0.64) | MTORCYP1A2CYP3A4CYP2C19OGG1 | |
| SCHEMBL4888895 | 0.87 | CYP1A2 (0.64) | MTORCYP1A2CYP3A4CYP2C19OGG1 | |
| SCHEMBL4878370 | 0.87 | KMT2A (0.45) | MTORNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4886123 | 0.87 | KMT2A (0.48) | MTORNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4886121 | 0.87 | KMT2A (0.48) | MTORNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4878364 | 0.87 | KMT2A (0.45) | MTORNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4903099 | 0.86 | MAPT (0.50) | MTORCYP1A2CYP3A4CYP2C19OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | MTOR 3042/4885CYP1A2 74/4885CYP3A4 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.