Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509969 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HSD17B10TSHRTP53 | |
| Fenthion SCHEMBL29441335 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Fenthion SCHEMBL6739014 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Fenthion SCHEMBL26907 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Fenthion SCHEMBL28673475 | 0.75 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| SCHEMBL12799246 | 0.73 | ALDH1A1 (0.67) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| Fenthion SCHEMBL1933208 | 0.73 | ALDH1A1 (0.81) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| SCHEMBL11778090 | 0.70 | ALDH1A1 (0.44) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| SCHEMBL11180796 | 0.70 | CYP3A4 (0.46) | ALDH1A1CYP3A4HSD17B10TSHRLMNA | |
| SCHEMBL11061618 | 0.69 | ALDH1A1 (0.57) | ALDH1A1CYP3A4HSD17B10TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080286473-A1 | Ice Adhesion Mitigation | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS | 2008-11-20 | — | — | US | disclosed |