SCHEMBL4876815

SCHEMBL4876815

C/C=C/C=C/COC(=O)CCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 3/20 0.38
KDM6B O15054 1/20 0.38
KDM5C P41229 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
LMNA P02545 3/20 0.36
FASN P49327 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 2/20 0.33
SLC15A2 Q16348 1/20 0.32
MAPK1 P28482 1/20 0.32
SLC13A3 Q8WWT9 1/20 0.32
OR51E2 Q9H255 1/20 0.32
SOAT1 P35610 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
PAM P19021 2/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16445870 1.00 EGLN1 (0.38) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL4876823 1.00 EGLN1 (0.38) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL27279321 0.88 EGLN1 (0.43) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL20646268 0.85 TSHR (0.46) LMNAALDH1A1TSHRSOAT1PAM
SCHEMBL2146119 0.83 ALDH1A1 (0.41) FASNALDH1A1TSHRSOAT1PAM
SCHEMBL2146116 0.83 ALDH1A1 (0.41) FASNALDH1A1TSHRSOAT1PAM
SCHEMBL5837085 0.83 CNR2 (0.33) SOAT1
SCHEMBL5837093 0.83 CNR2 (0.33) SOAT1
SCHEMBL10292270 0.82 LMNA (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
Adipic Acid SCHEMBL27941078 0.81 LMNA (0.44) LMNAALDH1A1TSHRMAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777198-B2 Method for producing cohesive polyacrylate adhesive compounds with a narrow molar mass distribution TESA SE (DE) 2017-10-03 US disclosed
US-9777198-B2 Method for producing cohesive polyacrylate adhesive compounds with a narrow molar mass distribution TESA SE (DE) 2017-10-03 US disclosed
EP-2780402-B1 METHOD FOR PRODUCING COHESIVE POLYACRYLATE ADHESIVE COMPOUNDS WITH A NARROW MOLAR MASS DISTRIBUTION TESA SE (DE) 2017-08-09 EP disclosed
EP-3030559-B1 URAZOLE COMPOUNDS UNIV GENT (BE) 2017-06-28 EP disclosed
US-9586935-B2 Urazole compounds UNIVERSITEIT GENT (BE) 2017-03-07 US disclosed
US-20160200707-A1 URAZOLE COMPOUNDS UNIVERSITEIT GENT (BE) 2016-07-14 US disclosed
EP-3030559-A1 URAZOLE COMPOUNDS Universiteit Gent (BE) 2016-06-15 EP disclosed
WO-2015018928-A1 URAZOLE COMPOUNDS UNIVERSITEIT GENT (BE) 2015-02-12 WO disclosed
US-20140341909-A1 CONJUGATION OF BIOMOLECULES USING DIELS-ALDER CYCLOADDITION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) 2014-11-20 US disclosed
US-20140329971-A1 Method for Producing Cohesive Polyacrylate Adhesive Compounds with a Narrow Molar Mass Distribution TESA SE (DE) 2014-11-06 US disclosed
US-20140329971-A1 Method for Producing Cohesive Polyacrylate Adhesive Compounds with a Narrow Molar Mass Distribution TESA SE (DE) 2014-11-06 US disclosed
WO-2013072121-A1 METHOD FOR PRODUCING COHESIVE POLYACRYLATE ADHESIVE COMPOUNDS WITH A NARROW MOLAR MASS DISTRIBUTION TESA SE (DE) 2013-05-23 WO disclosed
US-20080008709-A1 Conjugation of biomolecules using Diels-Alder cycloaddition The Government of the U.S. as represented by the Secretary of the Dept. of Health and Human 2008-01-10 US disclosed
US-7211445-B2 Immunology, diagnosis, therapy; complex of carbohydrate and protein; immobilization THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2007-05-01 US disclosed
US-20040082067-A1 Immunology, diagnosis, therapy; complex of carbohydrate and protein; immobilization THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HLTH. AND HUMAN SERVICE 2004-04-29 US disclosed
US-6673905-B2 FOR COVALENTLY LINKING CARBOHYDRATES AND PROTEINS UNDER NEUTRAL CONDITIONS, BY ATTACHING DOUBLE BONDS TO A CARRIER PROTEIN, AND ATTACHING A CONJUGATED DIENE TO A CARBOHYDRATE HAPTEN, THEN COUPLING; VACCINES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2004-01-06 US disclosed
US-20020068818-A1 Conjugation of biomolecules using diels-alder cycloaddition POZSGAY VINCE (US) 2002-06-06 US disclosed
US-20020051788-A1 For covalently linking carbohydrates and proteins under neutral conditions, by attaching double bonds to a carrier protein, and attaching a conjugated diene to a carbohydrate hapten, then coupling; vaccines HEALTH AND HUMAN SERVICES, DEPARTMENT OF, GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, THE 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140341909-A1 CONJUGATION OF BIOMOLECULES USING DIELS-ALDER CYCLOADDITION DERA, DCLRE1A, CD2BP2 EGLN1 3428/4885KDM6B 4683/4885KDM5C 4195/4885
US-20020068818-A1 Conjugation of biomolecules using diels-alder cycloaddition DERA, DCLRE1A, CD2BP2 EGLN1 3428/4885KDM6B 4683/4885KDM5C 4195/4885
US-20020051788-A1 For covalently linking carbohydrates and proteins under neutral conditions, by attaching double bonds to a carrier protein, and attaching a conjugated diene to a carbohydrate hapten, then coupling; vaccines DCLRE1A, DERA, LY96 EGLN1 2753/4885KDM6B 4566/4885KDM5C 3094/4885
US-20080008709-A1 Conjugation of biomolecules using Diels-Alder cycloaddition DERA, DCLRE1A, CD2BP2 EGLN1 3428/4885KDM6B 4683/4885KDM5C 4195/4885
US-20160200707-A1 URAZOLE COMPOUNDS UFL1, UFM1, SULT1E1 EGLN1 4389/4885KDM6B 2439/4885KDM5C 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.