Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PAM | P19021 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16445870 | 1.00 | EGLN1 (0.38) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL4876815 | 1.00 | EGLN1 (0.38) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL27279321 | 0.88 | EGLN1 (0.43) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL20646268 | 0.85 | TSHR (0.46) | LMNAALDH1A1TSHRSOAT1PAM | |
| SCHEMBL2146119 | 0.83 | ALDH1A1 (0.41) | FASNALDH1A1TSHRSOAT1PAM | |
| SCHEMBL2146116 | 0.83 | ALDH1A1 (0.41) | FASNALDH1A1TSHRSOAT1PAM | |
| SCHEMBL5837085 | 0.83 | CNR2 (0.33) | SOAT1 | |
| SCHEMBL5837093 | 0.83 | CNR2 (0.33) | SOAT1 | |
| SCHEMBL10292270 | 0.82 | LMNA (0.45) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Adipic Acid SCHEMBL27941078 | 0.81 | LMNA (0.44) | LMNAALDH1A1TSHRMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080008709-A1 | Conjugation of biomolecules using Diels-Alder cycloaddition | The Government of the U.S. as represented by the Secretary of the Dept. of Health and Human | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080008709-A1 | Conjugation of biomolecules using Diels-Alder cycloaddition | DERA, DCLRE1A, CD2BP2 | EGLN1 3428/4885KDM6B 4683/4885KDM5C 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.