SCHEMBL4876859

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11561454	0.88	HMGB1 (0.46)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL27777852	0.85	HMGB1 (0.55)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL10785106	0.83	LDHA (0.48)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL29031971	0.83	CYP3A4 (0.50)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL4641265	0.83	LDHA (0.48)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL14989265	0.83	KDM4E (0.44)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL6904405	0.83	KDM4E (0.45)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL8830205	0.83	LDHA (0.52)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL31315038	0.83	HMGB1 (0.52)	LDHALDHBHMGB1CXCL12ALDH1A1
	SCHEMBL8830153	0.83	HMGB1 (0.52)	LDHALDHBHMGB1CXCL12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.