Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 3/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 3/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876883 | 1.00 | KMT2A (0.37) | KMT2AACKR3SCN1ASCN2ASCN3A | |
| SCHEMBL4876166 | 0.95 | KMT2A (0.39) | KMT2AACKR3SCN1ASCN2ASCN3A | |
| SCHEMBL4876172 | 0.95 | KMT2A (0.39) | KMT2AACKR3SCN1ASCN2ASCN3A | |
| SCHEMBL4875278 | 0.94 | KMT2A (0.40) | KMT2AACKR3SCN1ASCN2ASCN3A | |
| SCHEMBL4875287 | 0.94 | KMT2A (0.40) | KMT2AACKR3SCN1ASCN2ASCN3A | |
| SCHEMBL4879052 | 0.91 | HTR1A (0.32) | NPC1RAB9A | |
| SCHEMBL4879060 | 0.91 | HTR1A (0.32) | NPC1RAB9A | |
| SCHEMBL4874083 | 0.90 | KMT2A (0.38) | KMT2AACKR3HTR1FHSD11B1 | |
| SCHEMBL4877665 | 0.90 | KMT2A (0.38) | KMT2AACKR3HTR1FHSD11B1 | |
| SCHEMBL4874077 | 0.90 | KMT2A (0.38) | KMT2AACKR3HTR1FHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081825-A1 | Nitrogen-Containing Heterocyclic Compounds and Medicinal Use Thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-03 | — | — | US | claimed |
| EP-1741702-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | claimed |
| US-20080081825-A1 | Nitrogen-Containing Heterocyclic Compounds and Medicinal Use Thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-1741702-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081825-A1 | Nitrogen-Containing Heterocyclic Compounds and Medicinal Use Thereof | MAPK1, NOS1, NOS2 | KMT2A 3886/4885ACKR3 94/4885SCN1A 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.