Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404037 | 1.00 | KCNH2 (0.43) | KCNH2SCN3AMASP2 | |
| SCHEMBL1094707 | 1.00 | KCNH2 (0.43) | KCNH2SCN3AMASP2 | |
| SCHEMBL4876900 | 1.00 | KCNH2 (0.43) | KCNH2SCN3AMASP2 | |
| SCHEMBL12055825 | 1.00 | KCNH2 (0.43) | KCNH2SCN3AMASP2 | |
| SCHEMBL405483 | 0.79 | F2 (0.52) | MASP2 | |
| SCHEMBL10287266 | 0.79 | F2 (0.52) | MASP2 | |
| SCHEMBL30890546 | 0.78 | KCNH2 (0.60) | KCNH2SCN3A | |
| SCHEMBL439924 | 0.75 | HDAC4 (0.60) | — | |
| SCHEMBL8869867 | 0.71 | DPP4 (0.47) | KCNH2SCN3A | |
| SCHEMBL8869859 | 0.71 | DPP4 (0.47) | KCNH2SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154988-A1 | Antibacterial agents | MRPL21, SI, PGLS | KCNH2 3106/4885SCN3A 3248/4885MASP2 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.