Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816628 | 0.85 | CYP1A2 (0.36) | ALDH1A1CTSKLMNACYP1A2NFKB1 | |
| SCHEMBL6237982 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CTSKLMNA | |
| SCHEMBL4880035 | 0.78 | CYP1A2 (0.31) | ALDH1A1CTSKLMNACYP1A2 | |
| SCHEMBL7543239 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP1A2 | |
| SCHEMBL4879664 | 0.76 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL11572262 | 0.72 | — | — | |
| SCHEMBL7535053 | 0.71 | — | — | |
| SCHEMBL29042611 | 0.71 | ALOX5 (0.30) | — | |
| SCHEMBL15922307 | 0.69 | TSHR (0.35) | ALDH1A1CTSKLMNA | |
| SCHEMBL11735435 | 0.69 | GBA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125556-A1 | Copolymerizing two norbornene monomers, one having a pendant trimethylsilyl or timethylsilylmethyl group, and the other having optional pendant halogen or alkyl groups in the presence of a palladium-based multicomponent catalyst containing palladium, phosphorus, ionic boron and ionic aluminum compounds | JSR CORPORATION (JP) | 2008-05-29 | — | — | US | disclosed |