Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868483 | 0.82 | ALDH1A1 (0.45) | MAPTLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4873209 | 0.75 | KMT2A (0.39) | MAPTLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4876785 | 0.75 | ALDH1A1 (0.45) | MAPTLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4868294 | 0.69 | THRB (0.39) | MAPTLMNACYP1A2ALDH1A1KMT2A | |
| SCHEMBL4873983 | 0.66 | HTR1A (0.43) | MAPTLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10284046 | 0.64 | MEN1 (0.67) | MAPTLMNACYP1A2CYP2C19PKM | |
| SCHEMBL4868226 | 0.64 | HSD17B10 (0.37) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL4874799 | 0.63 | TP53 (0.36) | LMNAALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL4872373 | 0.62 | ALDH1A1 (0.43) | MAPTLMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL14385851 | 0.62 | ALDH1A1 (0.73) | MAPTLMNACYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393845-B2 | Heteroaryl derivates, their preparation and use | H. LUNDBECK A/S (DK) | 2008-07-01 | — | — | US | disclosed |
| US-20080027071-A1 | Novel heteroaryl derivatives, their preparation and use | H. LUNDBECK A/S (DK) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027071-A1 | Novel heteroaryl derivatives, their preparation and use | GRIN2C, GRIN2B, HTR2C | MAPT 1172/4885LMNA 3342/4885CYP1A2 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.