SCHEMBL4878263

SCHEMBL4878263

CCCCCC/C=C/P(=O)(O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 1/20 0.47
SOAT1 P35610 1/20 0.47
FAAH O00519 3/20 0.45
EPHX2 P34913 2/20 0.45
CETP P11597 4/20 0.44
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
CES1 P23141 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
DUSP3 P51452 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41
PTPN7 P35236 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4878268 1.00 SOAT2 (0.47) SOAT2SOAT1FAAHEPHX2CETP
SCHEMBL31590883 1.00 SOAT2 (0.47) SOAT2SOAT1FAAHEPHX2CETP
SCHEMBL31590628 0.94 TSHR (0.46) SOAT2SOAT1CETPALOX15TSHR
SCHEMBL31590664 0.87 TSHR (0.48) ALOX15TSHR
SCHEMBL4609010 0.84 SOAT2 (0.46) SOAT2SOAT1FAAHEPHX2TSHR
SCHEMBL4609004 0.84 SOAT2 (0.46) SOAT2SOAT1FAAHEPHX2TSHR
SCHEMBL1287657 0.80 TSHR (0.52) ALOX15TSHR
SCHEMBL21518324 0.79 FAAH (0.44) SOAT2SOAT1FAAHEPHX2TSHR
SCHEMBL31590296 0.79 EPHX2 (0.49) SOAT2SOAT1FAAHEPHX2CETP
SCHEMBL4606349 0.78 AOX1 (0.44) SOAT2SOAT1FAAHEPHX2CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080091040-A1 Optically active alkenylphosphinic acid ester and process for producing the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2008-04-17 US disclosed
EP-1375505-B1 OPTICALLY ACTIVE ALKENYLPHOSPHINIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME JAPAN SCIENCE & TECH AGENCY (JP) 2006-09-13 EP disclosed
US-20040092752-A1 Optically active alkenylphosphinic acid esters and process for producing the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-05-13 US disclosed
EP-1375505-A1 OPTICALLY ACTIVE ALKENYLPHOSPHINIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME Japan Science and Technology Corporation (JP) 2004-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092752-A1 Optically active alkenylphosphinic acid esters and process for producing the same APEH, ACOX1, PHOSPHO1 SOAT2 369/4885SOAT1 310/4885FAAH 748/4885
US-20080091040-A1 Optically active alkenylphosphinic acid ester and process for producing the same PHOSPHO1, APEH, ACP3 SOAT2 247/4885SOAT1 171/4885FAAH 2163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.