Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 12/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021275 | 0.92 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP1A2CYP2D6KDM4E | |
| SCHEMBL4878638 | 0.83 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP1A2CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL4888748 | 0.79 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP1A2CYP2D6KDM4E | |
| SCHEMBL4881228 | 0.77 | CYP3A4 (0.61) | CYP3A4CYP2C9CYP1A2CYP2D6KDM4E | |
| SCHEMBL4885850 | 0.71 | CYP3A4 (0.77) | CYP3A4CYP2C9CYP1A2CYP2D6MCHR1 | |
| SCHEMBL4888544 | 0.69 | CYP3A4 (0.55) | CYP3A4CYP2C9CYP1A2CYP2D6LMNA | |
| SCHEMBL14021269 | 0.69 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP1A2CYP2D6KDM4E | |
| SCHEMBL4881063 | 0.64 | CYP3A4 (0.65) | CYP3A4CYP2C9CYP1A2CYP2D6MCHR1 | |
| SCHEMBL4890938 | 0.64 | CYP3A4 (0.61) | CYP3A4CYP2C9CYP1A2CYP2D6MCHR1 | |
| SCHEMBL4888752 | 0.63 | CYP3A4 (0.42) | CYP3A4CYP2C9CYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | GLAXO GROUP LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | ALPI, PYGL, PPIP5K2 | CYP3A4 215/4885CYP2C9 1357/4885CYP1A2 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.