Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.67 |
| ▸ | CTSS | P25774 | 6/20 | 0.67 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214620 | 0.87 | CTSK (0.69) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL3214617 | 0.87 | CTSK (0.69) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL12069039 | 0.87 | CTSK (0.69) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL4598033 | 0.85 | CTSK (0.67) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL15626081 | 0.85 | CTSK (0.67) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL12880513 | 0.85 | CTSK (0.67) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL15671568 | 0.85 | CTSK (0.67) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL15671569 | 0.85 | CTSK (0.67) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL4598036 | 0.85 | CTSK (0.67) | CTSKCTSSS1PR3SCN9ACTSL | |
| SCHEMBL16171655 | 0.84 | CTSK (0.66) | CTSKCTSSS1PR3SCN9ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154988-A1 | Antibacterial agents | MRPL21, SI, PGLS | CTSK 430/4885CTSS 300/4885S1PR3 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.