Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878034 | 0.83 | ALDH1A1 (0.61) | MAPTSMN1; SMN2ALDH1A1KDM4ETAAR1 | |
| SCHEMBL14557080 | 0.78 | L3MBTL1 (0.57) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19538865 | 0.77 | KMT2A (0.59) | MAPTSMN1; SMN2ALDH1A1KDM4ETAAR1 | |
| SCHEMBL9772348 | 0.74 | PRKCI (0.45) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL4771735 | 0.74 | BCHE (0.56) | MAPTSMN1; SMN2ALDH1A1KDM4ETAAR1 | |
| SCHEMBL11209828 | 0.73 | BCHE (0.67) | KDM4EMEN1KMT2ASIGMAR1 | |
| SCHEMBL29643279 | 0.73 | BCHE (0.67) | KDM4EMEN1KMT2ASIGMAR1 | |
| SCHEMBL4881337 | 0.72 | ALDH1A1 (0.69) | MAPTSMN1; SMN2ALDH1A1KDM4ETAAR1 | |
| SCHEMBL25954789 | 0.72 | KMT2A (0.56) | MAPTSMN1; SMN2ALDH1A1KDM4ETAAR1 | |
| SCHEMBL11712251 | 0.71 | LMNA (0.67) | MAPTSMN1; SMN2ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536655-B | Polycyclic compound for inhibiting RNA helicase DHX33 | 深圳开悦生命科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-115536655-A | Polycyclic compound for inhibiting RNA helicase DHX33 | 深圳开悦生命科技有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-103483237-B | Method for preparing pyrrole derivatives by catalyzing double-sulfonate ionic liquid | UNIV ANHUI TECHNOLOGY | 2015-04-08 | — | — | CN | disclosed |
| CN-103483237-A | Method for preparing pyrrole derivatives by catalyzing double-sulfonate ionic liquid | UNIV ANHUI TECHNOLOGY | 2014-01-01 | — | — | CN | disclosed |
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | IMMUSOL INCORPORATED (US) | 2008-11-13 | — | — | US | disclosed |
| EP-1841428-A1 | NOVEL QUINOLINIUM SALTS AND DERIVATIVES | Immusol Incorporated (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006078754-A1 | NOVEL QUINOLINIUM SALTS AND DERIVATIVES | IMMUSOL INCORPORATED (US) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | NQO2, MCL1, KRAS | MAPT 2491/4885SMN1; SMN2 4426/4885ALDH1A1 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.