SCHEMBL4879282

SCHEMBL4879282

CCC(/C=C/c1ccccc1)=C(/C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
NPC1 O15118 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 3/20 0.50
HDAC3 O15379 3/20 0.50
HDAC4 P56524 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
PLIN1 O60240 2/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
RECQL P46063 2/20 0.50
PLIN5 Q00G26 2/20 0.50
ABHD5 Q8WTS1 2/20 0.50
TNKS O95271 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL905409 1.00 GLA (0.56) GLATDP1NPC1L3MBTL1ALDH1A1
SCHEMBL14351521 0.87 GLA (0.53) GLATDP1NPC1L3MBTL1ALDH1A1
SCHEMBL27360823 0.84 GLA (0.50) GLATDP1NPC1L3MBTL1ALDH1A1
SCHEMBL393959 0.84 HDAC3 (0.50) GLATDP1NPC1L3MBTL1ALDH1A1
SCHEMBL4637965 0.83 GLA (0.53) GLATDP1NPC1L3MBTL1ALDH1A1
SCHEMBL8667763 0.83 THRB (0.59) NPC1L3MBTL1ALDH1A1HDAC3HDAC4
SCHEMBL14351392 0.83 EGFR (0.52) GLATDP1NPC1L3MBTL1ALDH1A1
SCHEMBL3806310 0.83 TDP1 (0.52) GLATDP1NPC1L3MBTL1ALDH1A1
SCHEMBL5573242 0.82 ALDH1A1 (0.63) GLATDP1NPC1L3MBTL1ALDH1A1
SCHEMBL2511760 0.82 GLA (0.51) GLATDP1NPC1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345125-B2 Silicone resin composition and molded product thereof NIPPON STEEL CHEMICAL CO., LTD. (JP) 2008-03-18 US disclosed
US-20060069216-A1 Silicone resin composition and molded product thereof NIPPON STEEL CHEMICAL CO., LTD. 2006-03-30 US disclosed
WO-2001066631-A1 USE OF AMINO-SUBSTITUTED HYDROXYBENZOPHENONES AS LIGHT-STABILITY AGENTS AND STABILIZERS FOR NON-LIVING ORGANIC MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2001-09-13 WO disclosed
EP-0080431-B1 SYNERGISTIC MIXTURE OF LOW AND HIGH MOLECULAR WEIGHT POLYALKYL PIPERIDINES CIBA-GEIGY AG (CH) 1986-09-24 EP disclosed
EP-0022079-B1 POLYALKYLPIPERIDYL UREAS, THEIR APPLICATION AS STABILIZERS AND POLYMERS THUS STABILIZED CIBA-GEIGY AG (CH) 1984-01-18 EP disclosed
EP-0080431-A2 Synergistic mixture of low and high molecular weight polyalkyl piperidines CIBA-GEIGY AG (CH) 1983-06-01 EP disclosed
EP-0057160-A1 2-(2-Hydroxyphenyl)-benzotriazoles, their use as ultraviolet stabilizers and their preparation CIBA-GEIGY AG (CH) 1982-08-04 EP disclosed
EP-0042358-A1 Organic sulphides and their use as stabilizers in organic materials CIBA-GEIGY AG (CH) 1981-12-23 EP disclosed
EP-0022079-A1 Polyalkylpiperidyl ureas, their application as stabilizers and polymers thus stabilized CIBA-GEIGY AG (CH) 1981-01-07 EP disclosed