SCHEMBL8667763

SCHEMBL8667763

CCC(C=Cc1ccc(OC)cc1)=C(C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
ATM Q13315 1/20 0.59
GSK3B P49841 2/20 0.58
F3 P13726 2/20 0.57
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
BACE1 P56817 1/20 0.54
HDAC3 O15379 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
BCHE P06276 1/20 0.52
CYP3A4 P08684 1/20 0.52
NFKB1 P19838 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
XDH P47989 1/20 0.51
TAS1R3 Q7RTX0 2/20 0.51
TAS1R1 Q7RTX1 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4879282 0.83 GLA (0.56) F3NPC1RAB9AHDAC3HDAC1
SCHEMBL905409 0.83 GLA (0.56) F3NPC1RAB9AHDAC3HDAC1
SCHEMBL856867 0.78 GSK3B (0.80) THRBATMGSK3BF3NPC1
SCHEMBL856866 0.78 GSK3B (0.80) THRBATMGSK3BF3NPC1
4-Methoxycinnamic Acid SCHEMBL28249256 0.76 THRB (0.86) THRBATMGSK3BF3NPC1
4-Methoxycinnamic Acid SCHEMBL6578185 0.76 THRB (0.93) THRBATMGSK3BF3NPC1
SCHEMBL1678195 0.76 THRB (0.73) THRBATMGSK3BF3NPC1
4-Methoxycinnamic Acid SCHEMBL6578183 0.76 THRB (0.93) THRBATMGSK3BF3NPC1
SCHEMBL1678197 0.76 THRB (0.73) THRBATMGSK3BF3NPC1
4-Methoxycinnamic Acid SCHEMBL58700 0.76 THRB (1.00) THRBATMGSK3BF3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975327-B2 Controlling morphology of block copolymers DOW CORNING CORPORATION (US) 2015-03-10 US disclosed
EP-2643413-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS Dow Corning Corporation (US) 2013-10-02 EP disclosed
US-20130231438-A1 Controlling Morphology of Block Copolymers DOW CORNING CORPORATION (US) 2013-09-05 US disclosed
WO-2012071330-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS DOW CORNING CORPORATION (US) 2012-05-31 WO disclosed