Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694580 | 0.86 | ENPP1 (0.53) | ENPP1SMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL4879793 | 0.85 | ENPP1 (0.52) | ENPP1SMN1; SMN2HTTGAA | |
| SCHEMBL5231751 | 0.72 | KDM4E (0.44) | ENPP1SMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL5227567 | 0.71 | MBOAT4 (0.40) | ALDH1A1GAAL3MBTL1LMNARAB9A | |
| SCHEMBL5672954 | 0.68 | ALDH1A1 (0.40) | ENPP1SMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL5593524 | 0.67 | GAA (0.47) | ENPP1SMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL1646899 | 0.65 | ALDH1A1 (0.50) | ENPP1SMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL3130141 | 0.65 | GAA (0.45) | SMN1; SMN2HTTGAA | |
| SCHEMBL5402153 | 0.65 | GAA (0.45) | SMN1; SMN2HTTGAA | |
| SCHEMBL3133063 | 0.65 | GAA (0.45) | SMN1; SMN2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188494-A1 | Use Of 5-Alkyl-6-Phenylalkyl-7-Aminoazolopyrimidines, Novel Azolopyrimidines, Processes For Their Preparation And Compositions Comprising Them | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188494-A1 | Use Of 5-Alkyl-6-Phenylalkyl-7-Aminoazolopyrimidines, Novel Azolopyrimidines, Processes For Their Preparation And Compositions Comprising Them | RRM2, PNP, NT5C3B | ENPP1 818/4885SMN1; SMN2 3970/4885HTT 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.