Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 11/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 11/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788930 | 0.98 | HSD11B1 (0.49) | HSD11B1TPSAB1TPSD1TPSG1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL23111949 | 0.87 | HSD11B1 (0.41) | HSD11B1TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL17479093 | 0.86 | TPSAB1 (0.44) | HSD11B1TPSAB1TPSD1TPSG1CA2 | |
| SCHEMBL22080031 | 0.84 | TP53 (0.42) | TPSAB1TPSD1TPSG1POLBMMP1 | |
| SCHEMBL20816231 | 0.84 | TPSAB1 (0.40) | HSD11B1TPSAB1TPSD1TPSG1CHRNB2 | |
| SCHEMBL29703400 | 0.83 | TPSAB1 (0.45) | HSD11B1TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL29703407 | 0.83 | TPSAB1 (0.45) | HSD11B1TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL5623233 | 0.83 | TPSAB1 (0.45) | HSD11B1TPSAB1TPSD1TPSG1CA2 | |
| SCHEMBL12520131 | 0.83 | TPSAB1 (0.45) | HSD11B1TPSAB1TPSD1TPSG1CA2 | |
| SCHEMBL28288403 | 0.83 | TPSAB1 (0.45) | HSD11B1TPSAB1TPSD1TPSG1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115505-A1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 AND/OR M4 RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-06-11 | — | — | WO | disclosed |
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | PFIZER INC | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | MCHR1, MCHR2, MC1R | HSD11B1 177/4885TPSAB1 501/4885TPSD1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.