Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888767 | 0.86 | GPR119 (0.30) | GPR119 | |
| SCHEMBL4887387 | 0.85 | — | — | |
| SCHEMBL4885449 | 0.80 | MCHR1 (0.48) | KCNH2 | |
| SCHEMBL4879972 | 0.79 | GPR119 (0.50) | GPR119 | |
| SCHEMBL1781268 | 0.71 | HRH4 (0.35) | KCNH2 | |
| SCHEMBL25232014 | 0.66 | CA1 (0.39) | — | |
| SCHEMBL30466332 | 0.66 | CA1 (0.39) | — | |
| SCHEMBL25277048 | 0.66 | CA1 (0.39) | — | |
| SCHEMBL25279448 | 0.64 | HTT (0.37) | — | |
| SCHEMBL25279449 | 0.64 | HTT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | PFIZER INC | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | MCHR1, MCHR2, MC1R | GPR119 61/4885KCNH2 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.