Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL741583 | 0.98 | OPRM1 (0.47) | OPRM1KMT2AMEN1CHRM2CHRM4 | |
| SCHEMBL19281773 | 0.98 | OPRM1 (0.47) | OPRM1KMT2AMEN1CHRM2CHRM4 | |
| Aminodiphenylmethane SCHEMBL9192661 | 0.91 | ALDH1A1 (0.44) | OPRM1KMT2AMEN1CHRM2CHRM4 | |
| SCHEMBL24238319 | 0.89 | OPRM1 (0.54) | OPRM1KMT2AMEN1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL5198335 | 0.89 | OPRM1 (0.41) | OPRM1KMT2AMEN1CHRM2CHRM4 | |
| SCHEMBL20133104 | 0.89 | OPRM1 (0.54) | OPRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL24238295 | 0.89 | OPRM1 (0.41) | OPRM1KMT2AMEN1CHRM2CHRM4 | |
| SCHEMBL24238338 | 0.89 | OPRM1 (0.54) | OPRM1KMT2AMEN1CHRM2CHRM4 | |
| SCHEMBL5745379 | 0.88 | CYP2D6 (0.47) | OPRM1KMT2AMEN1CHRM2CHRM4 | |
| SCHEMBL2267354 | 0.84 | L3MBTL3 (0.53) | OPRM1KMT2AMEN1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118356774-B | Low-energy-consumption high-selectivity composite desulfurization solvent and preparation method thereof | 江苏创新石化有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-115650893-B | Synthesis method of 1-benzhydryl azetidine-3-one | 南通华祥医药科技有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-118356774-A | Low-energy-consumption high-selectivity composite desulfurization solvent and preparation method thereof | 江苏创新石化有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-116943408-B | Hindered amine composite desulfurizing agent and preparation method thereof | 江苏创新石化有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-116943408-A | Hindered amine composite desulfurizing agent and preparation method thereof | 江苏创新石化有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-115650893-A | Synthesis method of 1-benzhydrylazetidin-3-one | 南通华祥医药科技有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-104292142-B | A kind of de- aryl method of N- aryl-heterocyclic butane | 天津大地康和医药技术有限公司 | 2019-05-14 | — | — | CN | claimed |
| CN-105461691-B | A kind of preparation method of Azelnidipine | 威海迪素制药有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-109053524-A | A kind of preparation method of N-Boc-3- hydroxy azetidine | 山东谛爱生物技术有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-106905212-A | A kind of process for synthesizing the ketone of 1 dibenzo-p-methyl-aza-cyclobutane 3 | 上海昂提生物科技有限公司 | 2017-06-30 | — | — | CN | claimed |
| CN-105461691-A | Preparation method of azelnidipine | WEIHAI DISU PHARMACEUTICAL CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-103130700-B | Preparation method of azelnidipine intermediate | SHENYANG J & HEALTH PHARAMACEUTICAL CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-104292142-A | Aryl removing method of N-aryl heterocyclic butane | TIANJIN DADI KANGHE MEDICAL TECHNOLOGY CO LTD | 2015-01-21 | — | — | CN | claimed |
| CN-103509003-A | Preparation method of azelnidipine | WEIHAI WEITAI PHARMACEUTICAL TECHNOLOGY DEV CO LTD | 2014-01-15 | — | — | CN | claimed |
| CN-102329259-B | Preparation method of (1-benzhydryl-3-azetidinol) cyanoacetate | NANJING UNIVERSITY OF TECHNOLOGY | 2013-09-18 | — | — | CN | claimed |
| CN-103130700-A | Preparation method of azelnidipine intermediate | SHENYANG J & HEALTH PHARMACEUTICAL CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-102329259-A | Preparation method of (1-benzhydryl-3-azetidinol) cyanoacetate | NANJING UNIVERSITY OF TECHNOLOGY | 2012-01-25 | — | — | CN | claimed |
| CN-101747249-A | Method for preparing intermediate of azetidine-typed medicaments | UNIV TONGJI | 2010-06-23 | — | — | CN | claimed |
| CN-101676263-A | Method for synthesizing N-tert-butoxycarbonyl group-3-hydroxy azetidine | TIANJIN APPTEC CO LTD | 2010-03-24 | — | — | CN | claimed |
| EP-0560905-B1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY | ROBINS CO INC A H (US) | 1994-10-19 | — | — | EP | claimed |