Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433853 | 0.72 | NOTUM (0.41) | NOTUM | |
| SCHEMBL11545484 | 0.70 | CYP1A2 (0.34) | — | |
| SCHEMBL12075564 | 0.68 | NOTUM (0.54) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL19856445 | 0.68 | KCNJ1 (0.40) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL6614477 | 0.68 | PIM1 (0.39) | MAPTPOLBALDH1A1LMNAHTT | |
| SCHEMBL11582420 | 0.67 | — | — | |
| SCHEMBL7902 | 0.64 | ALDH1A1 (0.47) | NOTUMMAPTALDH1A1LMNAHTT | |
| SCHEMBL8021654 | 0.63 | — | — | |
| SCHEMBL17725689 | 0.62 | KCNJ1 (0.50) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL21379821 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874303-A1 | PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS | GLAXO GROUP LIMITED (GB) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006114313-A1 | PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS | GLAXO GROUP LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |
| CN-1069392-A | Herbicidal composition for paddy fields | DU PONT (US) | 1993-03-03 | — | — | CN | disclosed |