Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122081 | 0.89 | MEN1 (0.45) | MEN1KMT2ACASP2TSHRFAAH | |
| SCHEMBL8447044 | 0.87 | TSHR (0.46) | MEN1KMT2ACASP2TSHRFAAH | |
| SCHEMBL12190482 | 0.84 | MEN1 (0.41) | MEN1KMT2ACASP2TSHRFAAH | |
| SCHEMBL10481544 | 0.84 | MEN1 (0.41) | MEN1KMT2ACASP2TSHRFAAH | |
| SCHEMBL35515 | 0.84 | CA12 (0.35) | MEN1KMT2ATSHRCA12CA1 | |
| SCHEMBL896888 | 0.84 | CA12 (0.35) | MEN1KMT2ATSHRCA12CA1 | |
| SCHEMBL28324754 | 0.84 | MEN1 (0.59) | MEN1KMT2ACASP2RECQL | |
| SCHEMBL16422258 | 0.82 | MEN1 (0.42) | MEN1KMT2ACASP2TSHRFAAH | |
| SCHEMBL6551654 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2ACASP2TSHRFAAH | |
| Methyl Alcohol SCHEMBL22551142 | 0.82 | CA12 (0.34) | MEN1KMT2ATSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375168-B2 | Protein compatible methods and compounds for controlling the morphology and shrinkage of silica derived from polyol-modified silanes | MCMASTER UNIVERSITY | 2008-05-20 | — | — | US | disclosed |
| US-20040249082-A1 | Protein compatible methods and compounds for controlling the morphology and shrinkage of silica derived from polyol-modified silanes | MCMASTER UNIVERSITY (CA) | 2004-12-09 | — | — | US | disclosed |
| US-6667016-B1 | Contacting aqueous solution of ions with hybrid gel obtained by polycondensing, in solvent comprising water, at least one functionalized silicon alkoxide with metallic alkoxide, separating gel from aqueous solution | COMMISSARIAT A L'ENERGIE ATOMIQUE AND COMPAGNIE GENERALE DES MATIERES NUCLEAIRES (FR) | 2003-12-23 | — | — | US | disclosed |