Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829782 | 0.94 | TSHR (0.41) | TSHRCASP2FAAHL3MBTL1NAAA | |
| SCHEMBL25768098 | 0.90 | FAAH (0.47) | TSHRCASP2FAAHNAAADNM1 | |
| SCHEMBL15168667 | 0.87 | EPHX2 (0.47) | TSHRCASP2FAAHMEN1KMT2A | |
| SCHEMBL4880451 | 0.87 | MEN1 (0.39) | TSHRCASP2FAAHL3MBTL1NAAA | |
| SCHEMBL443249 | 0.85 | NAAA (0.46) | TSHRCASP2FAAHNAAADNM1 | |
| SCHEMBL28414246 | 0.85 | FAAH (0.56) | CASP2FAAHL3MBTL1NAAADNM1 | |
| SCHEMBL5898601 | 0.85 | CASP2 (0.56) | TSHRCASP2FAAHNAAADNM1 | |
| SCHEMBL12190573 | 0.84 | SLC6A5 (0.46) | TSHRCASP2FAAHNAAADNM1 | |
| SCHEMBL16678373 | 0.84 | NAAA (0.45) | TSHRCASP2FAAHNAAADNM1 | |
| SCHEMBL22028652 | 0.84 | FAAH (0.58) | CASP2FAAHL3MBTL1NAAADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919523-A | Derivatization of solid supports and methods for oligomer synthesis | AFFYMETRIX, INC. (US) | 1999-07-06 | — | — | US | disclosed |
| US-5624711-A | AFFIXING FUNCTIONAL SITES TO THE SURFACE OF A SOLID SUBSTRATE | AFFYMAX TECHNOLOGIES, N.V. (NL) | 1997-04-29 | — | — | US | disclosed |