Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122081 | 0.87 | MEN1 (0.45) | MEN1KMT2ACASP2RECQLTSHR | |
| SCHEMBL10481544 | 0.86 | MEN1 (0.41) | MEN1KMT2ACASP2RECQLTSHR | |
| SCHEMBL28324754 | 0.85 | MEN1 (0.59) | MEN1KMT2ACASP2RECQL | |
| SCHEMBL4880451 | 0.84 | MEN1 (0.39) | MEN1KMT2ACASP2RECQLTSHR | |
| SCHEMBL25768098 | 0.84 | FAAH (0.47) | MEN1KMT2ACASP2RECQLTSHR | |
| SCHEMBL6551654 | 0.84 | ALDH1A1 (0.52) | MEN1KMT2ACASP2RECQLTSHR | |
| SCHEMBL16422258 | 0.84 | MEN1 (0.42) | MEN1KMT2ACASP2RECQLTSHR | |
| SCHEMBL502431 | 0.82 | MEN1 (0.41) | MEN1KMT2ACASP2RECQLTSHR | |
| SCHEMBL5898601 | 0.82 | CASP2 (0.56) | MEN1KMT2ACASP2TSHRFAAH | |
| SCHEMBL896888 | 0.81 | CA12 (0.35) | MEN1KMT2ATSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8029577-B2 | Lightening and/or dyeing of human keratin fibres via a composition comprising a particular amino silicon compound and composition and device | L'OREAL S.A. (FR) | 2011-10-04 | — | — | US | disclosed |
| US-7909889-B2 | Lightening and/or coloring human keratin fibers using at least one aminotrialkoxy silane or at least one aminotrialkenyloxy silane composition | L'OREAL S.A. (FR) | 2011-03-22 | — | — | US | disclosed |
| US-7905927-B2 | Method for lightening and/or coloring human keratin fibers using a composition comprising an aminotrialkoxy silane or aminotrialkenyloxy silane compound and device | L'OREAL, SA (FR) | 2011-03-15 | — | — | US | disclosed |
| US-20100303748-A1 | METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | disclosed |
| US-20100297049-A1 | LIGHTENING AND/OR DYEING OF HUMAN KERATIN FIBRES BY MEANS OF A COMPOSITION COMPRISING A PARTICULAR AMINO SILICON COMPOUND AND COMPOSITION AND DEVICE | L'OREAL S.A. (FR) | 2010-11-25 | — | — | US | disclosed |
| US-20100275387-A1 | LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303748-A1 | METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE | KRT18, FABP4, APMAP | MEN1 4698/4885KMT2A 1543/4885CASP2 3226/4885 |
| US-20100275387-A1 | LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION | KRT18, FABP4, ALDH7A1 | MEN1 4644/4885KMT2A 1239/4885CASP2 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.