Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HPN | P05981 | 1/20 | 0.65 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942721 | 0.98 | ALOX15 (0.63) | ALOX15MAPTHPNSIRT5CA2 | |
| SCHEMBL1116372 | 0.95 | ALOX15 (0.65) | ALOX15MAPTHPNSIRT5CA2 | |
| SCHEMBL1116345 | 0.91 | ALOX15 (0.71) | ALOX15MAPTHPNSIRT5CA2 | |
| SCHEMBL3177529 | 0.81 | ALOX15 (0.71) | ALOX15MAPTHPNSIRT5CA2 | |
| SCHEMBL11798530 | 0.79 | CA2 (0.47) | ALOX15MAPTHPNSIRT5CA2 | |
| Probucol SCHEMBL5143451 | 0.79 | HPN (1.00) | ALOX15MAPTHPNSIRT5CA2 | |
| SCHEMBL8311264 | 0.79 | MAPT (0.68) | ALOX15MAPTHPNSIRT5CA2 | |
| Probucol SCHEMBL4150 | 0.79 | HPN (1.00) | ALOX15MAPTHPNSIRT5CA2 | |
| SCHEMBL4595518 | 0.78 | CYP2C9 (0.61) | ALOX15MAPTHPNSIRT5CA2 | |
| SCHEMBL6520594 | 0.78 | ALOX15 (0.55) | ALOX15MAPTHPNSIRT5CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119672-A1 | Method for Producing 2,6-Di-Tert-Butyl-4-Mercaptophenol and 4,4'-Isopropylidenedithiobis [2,6-Di-Tert-Butylphenol] | SUMITOMO CHEMICAL COMPANY, LIMITED | 2008-05-22 | — | — | US | disclosed |
| EP-1849768-A1 | METHODS FOR PRODUCING 2,6-DI-TERT-BUTYL-4-MERCAPTOPHENOL AND 4,4'-ISOPROPYLIDENEDITHIOBIS[2,6-DI-TERT-BUTYLPHENOL] | Sumitomo Chemical Company, Limited (JP) | 2007-10-31 | — | — | EP | disclosed |