Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16978269 | 0.86 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL4881440 | 0.84 | TSHR (0.50) | ALDH1A1TSHRSMN1; SMN2LMNAGAA | |
| SCHEMBL301433 | 0.81 | TSHR (0.51) | ALDH1A1TSHRL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL302645 | 0.80 | MAPT (0.50) | ALDH1A1TSHRSMN1; SMN2GAAHSD17B10 | |
| SCHEMBL617437 | 0.80 | MAPT (0.43) | ALDH1A1TSHRSMN1; SMN2HSD17B10POLB | |
| SCHEMBL17322958 | 0.79 | GAA (0.58) | ALDH1A1TSHRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12989912 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5836968 | 0.78 | PTGS1 (0.49) | ALDH1A1SMN1; SMN2GAAKMT2ATDP1 | |
| SCHEMBL5837295 | 0.77 | HPGD (0.39) | ALDH1A1TSHRL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL14889325 | 0.76 | TSHR (0.47) | ALDH1A1TSHRL3MBTL1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293821-A1 | Cooling compositions | MOZA ASHOK K | 2008-11-27 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-7030273-B1 | Compounds with physiological cooling effect | QAROMA, INC (US) | 2006-04-18 | — | — | US | disclosed |