Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889325 | 0.94 | TSHR (0.47) | TSHRHPGDHTTRAB9ANPC1 | |
| SCHEMBL4880337 | 0.90 | MEN1 (0.42) | TSHRHPGDHTTRAB9ANPC1 | |
| SCHEMBL302645 | 0.89 | MAPT (0.50) | TSHRHPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL617437 | 0.89 | MAPT (0.43) | TSHRSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL4881440 | 0.83 | TSHR (0.50) | TSHRHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL21090517 | 0.82 | TSHR (0.49) | TSHRHPGDHTTRAB9ANPC1 | |
| SCHEMBL4881902 | 0.81 | ALDH1A1 (0.54) | TSHRHPGDHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4873828 | 0.78 | MAPT (0.41) | TSHRHPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL18287170 | 0.77 | EPHX1 (0.59) | SMN1; SMN2KMT2A | |
| SCHEMBL13432065 | 0.77 | HPGD (0.54) | TSHRHPGDHTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079321-B1 | COOLING CONFECTIONERIES AND BEVERAGES | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2013-05-01 | — | — | EP | claimed |
| US-20110159141-A1 | COOLING CONFECTIONERIES AND BEVERAGES | INTERCONTINENTAL GREAT BRANDS LLC | 2011-06-30 | — | — | US | claimed |
| EP-2079321-A1 | COOLING CONFECTIONERIES AND BEVERAGES | Cadbury Adams USA LLC (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008039522-A1 | COOLING CONFECTIONERIES AND BEVERAGES | CADBURY ADAMS USA LLC (US) | 2008-04-03 | — | — | WO | claimed |
| EP-2375912-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF THROAT DISCOMFORT | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2017-08-23 | — | — | EP | disclosed |
| US-20130330396-A1 | METHODS FOR THE TREATMENT OF THROAT DISCOMFORT | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2013-12-12 | — | — | US | disclosed |
| US-20130216648-A1 | CHEWING GUM COMPOSITIONS PROVIDING FLAVOR RELEASE PROFILES | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2013-08-22 | — | — | US | disclosed |
| EP-2613649-A1 | CHEWING GUM COMPOSITIONS PROVIDING FLAVOR RELEASE PROFILES | Kraft Foods Global Brands LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| US-20130156885-A1 | CHEWING GUM CONTAINING COMBINATIONS OF PHYSIOLOGICAL COOLING AGENTS | WM. WRIGLEY JR. COMPANY | 2013-06-20 | — | — | US | disclosed |
| EP-2079321-B1 | COOLING CONFECTIONERIES AND BEVERAGES | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2582252-A1 | CHEWING GUM CONTAINING COMBINATIONS OF PHYSIOLOGICAL COOLING AGENTS | Wm. Wrigley Jr. Company (US) | 2013-04-24 | — | — | EP | disclosed |
| US-20120114735-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF THROAT DISCOMFORT | INTERCONTINENTAL GREAT BRANDS LLC | 2012-05-10 | — | — | US | disclosed |
| WO-2010102191-A1 | CHEWING GUM COMPOSITIONS PROVIDING FLAVOR RELEASE PROFILES | CADBURY ADAMS USA LLC (US) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010083133-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF THROAT DISCOMFORT | CADBURY ADAMS USA LLC (US) | 2010-07-22 | — | — | WO | disclosed |
| EP-2079321-A1 | COOLING CONFECTIONERIES AND BEVERAGES | Cadbury Adams USA LLC (US) | 2009-07-22 | — | — | EP | disclosed |
| US-20080293821-A1 | Cooling compositions | MOZA ASHOK K | 2008-11-27 | — | — | US | disclosed |
| WO-2008039522-A1 | COOLING CONFECTIONERIES AND BEVERAGES | CADBURY ADAMS USA LLC (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-7030273-B1 | Compounds with physiological cooling effect | QAROMA, INC (US) | 2006-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130330396-A1 | METHODS FOR THE TREATMENT OF THROAT DISCOMFORT | TAS2R43, TAS2R14, TAS2R31 | TSHR 2530/4885HPGD 1593/4885HTT 2391/4885 |
| US-20120114735-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF THROAT DISCOMFORT | TAS2R43, TAS2R14, TAS2R8 | TSHR 2708/4885HPGD 1633/4885HTT 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.