Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | POR | P16435 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30806439 | 0.81 | TAAR1 (0.39) | FFAR4MAPTTAAR1ALDH1A1HPGD | |
| SCHEMBL4547157 | 0.81 | MAPT (0.41) | GABRA1GABRB2MAPTRXFP1ALDH1A1 | |
| SCHEMBL2291344 | 0.81 | TAAR1 (0.39) | FFAR4MAPTTAAR1ALDH1A1HPGD | |
| SCHEMBL24199851 | 0.80 | FFAR4 (0.38) | FFAR4MAPTRAB9AAMY1A | |
| SCHEMBL598593 | 0.79 | TAAR1 (0.44) | MAPTRXFP1TAAR1NQO1POR | |
| SCHEMBL30831862 | 0.79 | NPSR1 (0.43) | FFAR4MAPTTAAR1ALDH1A1HPGD | |
| SCHEMBL13507390 | 0.79 | TAAR1 (0.47) | FFAR4TAAR1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2790749 | 0.79 | AMY1A (0.39) | FFAR4MAPTTAAR1ALDH1A1HPGD | |
| SCHEMBL13967762 | 0.79 | NPSR1 (0.43) | FFAR4MAPTTAAR1ALDH1A1HPGD | |
| SCHEMBL11809716 | 0.79 | IDO1 (0.41) | FFAR4MAPTTAAR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025897-A1 | CRYSTALLINE HYDRATE OF A JAK INHIBITOR COMPOUND | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2024-01-25 | — | — | US | disclosed |
| US-20230322774-A1 | DIMETHYL AMINO AZETIDINE AMIDES AS JAK INHIBITORS | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2023-10-12 | — | — | US | disclosed |
| US-11713315-B2 | 5 to 7 membered heterocyclic amides as JAK inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-11702415-B2 | Crystalline hydrate of a JAK inhibitor compound | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-07-18 | — | — | US | disclosed |
| EP-3354651-B1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2021-01-06 | — | — | EP | disclosed |
| CN-109912457-A | A kind of preparation method of 2,6- diethyl -4- aminomethyl phenyl malononitrile | 浙江中山化工集团股份有限公司 | 2019-06-21 | — | — | CN | disclosed |
| EP-3212643-B1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2019-03-20 | — | — | EP | disclosed |
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| EP-3354651-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF ROR-GAMMA-T | Janssen Pharmaceutica N.V. (BE) | 2018-08-01 | — | — | EP | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150038707-A1 | PROCESS FOR MAKING CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LLC | 2015-02-05 | — | — | US | disclosed |
| US-20150031891-A1 | BIS-QUARTERNARY CINCHONA ALKALOID SALTS AS ASYMMETRIC PHASE TRANSFER CATALYSTS | MERCK SHARP & DOHME CORP. (US) | 2015-01-29 | — | — | US | disclosed |
| US-20090192138-A1 | COMPOUNDS | BAESCHLIN DANIEL KASPAR | 2009-07-30 | — | — | US | disclosed |
| US-20090192138-A1 | COMPOUNDS | BAESCHLIN DANIEL KASPAR | 2009-07-30 | — | — | US | disclosed |
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | GLAXO GROUP LIMITED (GB) | 2008-10-16 | — | — | US | disclosed |
| EP-1861095-A1 | DERIVATIVES OF IMIDAZO(1,2-A)PYRIDINE USEFUL AS MEDICAMENTS FOR TREATING GASTROINTESTINAL DISEASES | GLAXO GROUP LIMITED (GB) | 2007-12-05 | — | — | EP | disclosed |
| US-7271270-B2 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-09-18 | — | — | US | disclosed |
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
| EP-1277734-B1 | 2- and 2,5-substituted phenylketo-enols | BAYER CROPSCIENCE AG (DE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2006100119-A1 | DERIVATIVES OF IMIDAZO (1,2-A) PYRIDINE USEFUL AS MEDICAMENTS FOR TREATING GASTROINTESTINAL DISEASES | GLAXO GROUP LIMITED (GB) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255358-A1 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases | ALPI, PYGL, PPIP5K2 | GABRA1 2030/4885GABRB2 2046/4885FFAR4 2431/4885 |
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | GPX1, POR, MGAM | GABRA1 2199/4885GABRB2 1885/4885FFAR4 4312/4885 |
| US-20150031891-A1 | BIS-QUARTERNARY CINCHONA ALKALOID SALTS AS ASYMMETRIC PHASE TRANSFER CATALYSTS | COASY, BCHE, CLK4 | GABRA1 3739/4885GABRB2 3738/4885FFAR4 4713/4885 |
| US-20230322774-A1 | DIMETHYL AMINO AZETIDINE AMIDES AS JAK INHIBITORS | JAK1, JAK2, JAK3 | GABRA1 945/4885GABRB2 1901/4885FFAR4 3324/4885 |
| US-11713315-B2 | 5 to 7 membered heterocyclic amides as JAK inhibitors | JAK1, JAK2, JAK3 | GABRA1 1242/4885GABRB2 2316/4885FFAR4 3808/4885 |
| US-20090192138-A1 | COMPOUNDS | DPP4, DPP3, DPP8 | GABRA1 3137/4885GABRB2 2677/4885FFAR4 489/4885 |
| US-11702415-B2 | Crystalline hydrate of a JAK inhibitor compound | JAK1, JAK2, JAK3 | GABRA1 3193/4885GABRB2 4441/4885FFAR4 2843/4885 |
| US-20240025897-A1 | CRYSTALLINE HYDRATE OF A JAK INHIBITOR COMPOUND | JAK1, JAK2, JAK3 | GABRA1 3193/4885GABRB2 4441/4885FFAR4 2843/4885 |
| US-20150038707-A1 | PROCESS FOR MAKING CGRP RECEPTOR ANTAGONISTS | CALCRL, CALCR, GRPR | GABRA1 117/4885GABRB2 73/4885FFAR4 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.