Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581767 | 0.80 | BRD4 (0.43) | FAAHBRD4NR1H2NR1H3 | |
| SCHEMBL18764834 | 0.80 | FAAH (0.42) | FAAHBRD4NR1H2NR1H3TBXA2R | |
| SCHEMBL6221657 | 0.77 | TBXA2R (0.47) | FAAHBRD4NR1H2TBXA2R | |
| SCHEMBL30828711 | 0.77 | BRD4 (0.44) | FAAHBRD4TBXA2R | |
| SCHEMBL6224033 | 0.77 | BRD4 (0.44) | FAAHBRD4TBXA2R | |
| SCHEMBL2795120 | 0.77 | BRD4 (0.39) | FAAHBRD4NR1H2NR1H3 | |
| SCHEMBL4385302 | 0.76 | TBXA2R (0.46) | FAAHBRD4AGTR1AGTR2TBXA2R | |
| SCHEMBL18765270 | 0.75 | BRD4 (0.46) | FAAHBRD4NR1H2TBXA2R | |
| SCHEMBL368032 | 0.75 | CYP1A2 (0.45) | FAAHNR1H2NR1H3TBXA2R | |
| SCHEMBL28721362 | 0.72 | NR1H2 (0.44) | FAAHNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045537-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-02-21 | — | — | US | disclosed |
| EP-1789045-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006023400-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045537-A1 | Chemical Compounds | CCR5, CXCR4, CXCR3 | FAAH 3111/4885IDH1 3104/4885PTGER4 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.