Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22186494 | 0.80 | HSD11B1 (0.33) | ALDH1A1TSHRKCNH2HSD11B1EPHX1 | |
| SCHEMBL3746835 | 0.78 | POLB (0.48) | TDP1ALDH1A1HSD11B1POLBMAPT | |
| SCHEMBL1897777 | 0.77 | TDP1 (0.42) | TDP1ALDH1A1ALOX5HSD11B1POLB | |
| SCHEMBL303265 | 0.76 | — | — | |
| SCHEMBL1896079 | 0.76 | TDP1 (0.46) | TDP1ALDH1A1ALOX5HSD11B1POLB | |
| SCHEMBL17294420 | 0.75 | — | — | |
| SCHEMBL16853131 | 0.74 | PLG (0.31) | POLB | |
| SCHEMBL19524977 | 0.74 | ALOX5 (0.38) | TDP1ALOX5 | |
| SCHEMBL19524958 | 0.74 | ALOX5 (0.38) | TDP1ALOX5 | |
| Hydrochloric Acid SCHEMBL2951045 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |