Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.63 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.63 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296114 | 0.88 | PLOD2 (0.65) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| SCHEMBL29786297 | 0.88 | PLOD2 (0.65) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Hydrochloric Acid SCHEMBL5419648 | 0.87 | PLOD2 (0.62) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Hydrochloric Acid SCHEMBL2821363 | 0.87 | PLOD2 (0.62) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Hydrochloric Acid SCHEMBL30113106 | 0.87 | PLOD2 (0.62) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Urea SCHEMBL15552231 | 0.83 | F7 (0.61) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Niacinamide SCHEMBL28262350 | 0.82 | F7 (0.76) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Niacinamide SCHEMBL30011021 | 0.82 | F7 (0.76) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Niacinamide SCHEMBL3714498 | 0.82 | F7 (0.76) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Niacin SCHEMBL4718565 | 0.82 | ALDH1A1 (0.78) | PLOD2PLOD3PLOD1ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007149395-A2 | 2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | AMPHORA DISCOVERY CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | ATP5ME, ATP5MG, ATP5MK | PLOD2 1840/4885PLOD3 3461/4885PLOD1 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.