Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12533893 | 0.84 | HSD11B1 (0.48) | SKP2HSD11B1RARBTSHRCTSV | |
| SCHEMBL919859 | 0.83 | HSD11B1 (0.47) | SKP2HSD11B1RARBTSHRCTSV | |
| SCHEMBL12638249 | 0.82 | HSD11B1 (0.48) | SKP2HSD11B1RARBTSHRCTSV | |
| SCHEMBL258162 | 0.82 | HSD11B1 (0.48) | SKP2HSD11B1RARBTSHRCTSV | |
| SCHEMBL20057200 | 0.81 | HSD11B1 (0.43) | SKP2HSD11B1RARBRAB9ASMN1; SMN2 | |
| SCHEMBL4883476 | 0.81 | SKP2 (0.36) | SKP2HSD11B1RARBRAB9ASMN1; SMN2 | |
| SCHEMBL13422650 | 0.79 | HSD11B1 (0.46) | SKP2HSD11B1RARBTP53TSHR | |
| SCHEMBL1033795 | 0.79 | SKP2 (0.44) | SKP2HSD11B1RARBRAB9ASMN1; SMN2 | |
| SCHEMBL10705373 | 0.78 | SKP2 (0.45) | SKP2HSD11B1RARBRAB9ASMN1; SMN2 | |
| SCHEMBL2539038 | 0.78 | CA2 (0.44) | SKP2HSD11B1SMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080268359-A1 | Single layered photoconductors | XEROX CORPORATION | 2008-10-30 | — | — | US | disclosed |