Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136252 | 0.78 | KDM4E (0.33) | BCHECNR2DDB1CRBNIDO1 | |
| SCHEMBL5313782 | 0.75 | KDM4E (0.51) | DDB1CRBNKDM4EALDH1A1LMNA | |
| SCHEMBL4143470 | 0.75 | KDM4E (0.51) | DDB1CRBNKDM4EALDH1A1LMNA | |
| SCHEMBL4143472 | 0.75 | KDM4E (0.51) | DDB1CRBNKDM4EALDH1A1LMNA | |
| SCHEMBL3296288 | 0.73 | BCHE (0.35) | BCHECNR2DDB1CRBNMALT1 | |
| SCHEMBL4186321 | 0.67 | SIGMAR1 (0.36) | KDM4EMEN1KMT2A | |
| SCHEMBL4186330 | 0.67 | SIGMAR1 (0.36) | KDM4EMEN1KMT2A | |
| SCHEMBL3983514 | 0.66 | ALDH1A1 (0.51) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL3983498 | 0.66 | ALDH1A1 (0.51) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL3293003 | 0.66 | IDO1 (0.36) | MALT1IDO1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | GLAXO GROUP LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| EP-1824497-A1 | MACROLONE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006050943-A1 | MACROLONE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | MRPL21, MRPS18A, MRPL19 | BCHE 3029/4885CNR2 4739/4885DDB1 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.