Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888911 | 0.90 | — | — | |
| SCHEMBL4880454 | 0.88 | — | — | |
| SCHEMBL4887403 | 0.86 | — | — | |
| SCHEMBL4881420 | 0.86 | KDM4E (0.30) | — | |
| SCHEMBL4890084 | 0.85 | — | — | |
| SCHEMBL4888094 | 0.83 | KDM5A (0.30) | KDM5A | |
| SCHEMBL4919305 | 0.79 | KDM5A (0.31) | KDM5AELANE | |
| SCHEMBL4885552 | 0.77 | — | — | |
| SCHEMBL5118207 | 0.76 | PKM (0.33) | KDM5AELANE | |
| SCHEMBL4888493 | 0.73 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167324-A1 | Thiazolymethyl and Oxazolylmethyl Heteroaryl Derivatives | NEUROGEN CORPORATION | 2008-07-10 | — | — | US | disclosed |
| US-20080167324-A1 | Thiazolymethyl and Oxazolylmethyl Heteroaryl Derivatives | NEUROGEN CORPORATION | 2008-07-10 | — | — | US | disclosed |
| US-20080167324-A1 | Thiazolymethyl and Oxazolylmethyl Heteroaryl Derivatives | NEUROGEN CORPORATION | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167324-A1 | Thiazolymethyl and Oxazolylmethyl Heteroaryl Derivatives | GABBR1, GABBR2, GABRA3 | KDM5A 3497/4885ELANE 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.