SCHEMBL4883987

SCHEMBL4883987

CSCCC(=O)NCc1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.66
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.59
EPHX2 P34913 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C19 P33261 1/20 0.59
ALDH1A1 P00352 3/20 0.58
HTT P42858 1/20 0.58
TP53 P04637 1/20 0.56
TSHR P16473 3/20 0.55
HPGD P15428 1/20 0.55
RECQL P46063 1/20 0.55
POLB P06746 1/20 0.54
TDP1 Q9NUW8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15678807 0.86 GAA (0.70) GAAMEN1KMT2AL3MBTL1EPHX2
SCHEMBL9517546 0.86 GAA (0.70) GAAMEN1KMT2AL3MBTL1EPHX2
SCHEMBL18704704 0.85 CA1 (0.67) GAACA1CA2MEN1KMT2A
SCHEMBL27891871 0.83 GAA (0.62) GAAMEN1KMT2AL3MBTL1EPHX2
SCHEMBL19542361 0.83 GAA (0.66) GAAMEN1KMT2AL3MBTL1EPHX2
SCHEMBL4890160 0.81 ALDH1A1 (0.67) GAACA1CA2MEN1KMT2A
SCHEMBL770934 0.80 CYP3A4 (0.87) GAAMEN1KMT2AL3MBTL1EPHX2
SCHEMBL2942358 0.80 MEN1 (0.96) GAAMEN1KMT2AL3MBTL1EPHX2
SCHEMBL21892071 0.79 GAA (0.60) GAAMEN1KMT2AL3MBTL1EPHX2
SCHEMBL5607428 0.79 GAA (0.70) GAAMEN1KMT2AL3MBTL1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US claimed
EP-1853352-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'Oréal (FR) 2007-11-14 EP claimed
WO-2006079568-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'OREAL (FR) 2006-08-03 WO claimed
US-10392621-B2 Multiaptamer target detection SOMALOGIC, INC. (US) 2019-08-27 US disclosed
US-20180187197-A1 Multiaptamer Target Detection SOMALOGIC OPERATING CO., INC. 2018-07-05 US disclosed
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US disclosed
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US disclosed
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US disclosed
EP-1853352-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'Oréal (FR) 2007-11-14 EP disclosed
WO-2006079568-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'OREAL (FR) 2006-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof KRT18, TYR, MC1R GAA 3721/4885CA1 2799/4885CA2 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.