Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031018 | 0.90 | ALDH1A1 (0.64) | GAAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL15678807 | 0.89 | GAA (0.70) | GAAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL4883987 | 0.86 | GAA (0.66) | GAAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL19542361 | 0.86 | GAA (0.66) | GAAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10031022 | 0.85 | AOC3 (0.62) | GAAKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL93948 | 0.85 | GAA (0.75) | GAAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10031037 | 0.85 | AOC3 (0.65) | GAAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL27891871 | 0.83 | GAA (0.62) | GAAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL2942358 | 0.82 | MEN1 (0.96) | GAAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL9516616 | 0.82 | CA1 (0.64) | KMT2AMEN1ALDH1A1HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5151447-A | Bactericides and fungicides | ROHM AND HAAS COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5023275-A | S-substituted beta-thioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |