Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.74 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747685 | 0.89 | ADRB1 (0.77) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Tulobuterol SCHEMBL29866527 | 0.85 | ADRB2 (1.00) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Tulobuterol SCHEMBL22970444 | 0.85 | ADRB2 (1.00) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Tulobuterol SCHEMBL30986127 | 0.85 | ADRB2 (1.00) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Tulobuterol SCHEMBL122692 | 0.85 | ADRB2 (1.00) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Tulobuterol SCHEMBL28319125 | 0.84 | ADRB2 (0.91) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Tulobuterol SCHEMBL123786 | 0.84 | BLM (1.00) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Tulobuterol SCHEMBL31356434 | 0.84 | BLM (1.00) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| SCHEMBL4626574 | 0.81 | ADRB1 (0.49) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| SCHEMBL4626380 | 0.81 | ADRB2 (0.50) | ADRB1ADRB2CYP2D6NFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | HRH3, OPRL1, HRH2 | ADRB1 198/4885ADRB2 131/4885CYP2D6 2783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.