Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flerobuterol SCHEMBL20819557 | 0.85 | ADRB1 (0.66) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Flerobuterol SCHEMBL249507 | 0.85 | ADRB1 (0.66) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Flerobuterol SCHEMBL30956705 | 0.85 | ADRB1 (0.66) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Flerobuterol SCHEMBL29356232 | 0.85 | ADRB1 (0.66) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Flerobuterol SCHEMBL10624514 | 0.84 | BLM (0.67) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| SCHEMBL4884062 | 0.81 | ADRB1 (0.74) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| SCHEMBL11136281 | 0.81 | ADRB2 (0.53) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| SCHEMBL11136288 | 0.81 | ADRB2 (0.53) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| Hydrochloric Acid SCHEMBL11134351 | 0.80 | ADRB2 (0.54) | ADRB1ADRB2BLM | |
| Fepradinol SCHEMBL151235 | 0.77 | KDM4E (0.55) | ADRB1ADRB2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | claimed |
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | disclosed |
| EP-1896393-A1 | THE TREATMENT OF INFLAMMATORY DISORDERS AND PAIN | Sosei R&D Ltd. (GB) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007003896-A1 | THE TREATMENT OF INFLAMMATORY DISORDERS AND PAIN | SOSEI R & D LTD. (GB) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | HRH3, OPRL1, HRH2 | ADRB1 198/4885ADRB2 131/4885CYP2D6 2783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.