Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888577 | 0.90 | HRH4 (0.56) | HRH4HRH3ALOX15 | |
| SCHEMBL4891849 | 0.90 | HRH4 (0.55) | HRH4HRH3ALOX15 | |
| SCHEMBL4888727 | 0.89 | HRH4 (0.47) | HRH4HRH3ALOX15 | |
| SCHEMBL4884675 | 0.87 | DRD3 (0.47) | HRH4HRH3ALOX15 | |
| SCHEMBL4884330 | 0.70 | HRH4 (0.60) | HRH4HRH3 | |
| SCHEMBL19994676 | 0.69 | SRD5A2 (0.48) | — | |
| SCHEMBL4814999 | 0.67 | GRIN1 (0.67) | — | |
| SCHEMBL4812905 | 0.66 | GRIN1 (0.66) | — | |
| SCHEMBL602139 | 0.66 | HRH4 (0.60) | HRH4HRH3 | |
| SCHEMBL4806542 | 0.66 | PIN1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300276-A1 | Heterocyclic Carboxylic Acide Amide Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-12-04 | — | — | US | claimed |
| EP-1771437-A1 | NEW HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010969-A1 | NEW HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | claimed |
| US-20080300276-A1 | Heterocyclic Carboxylic Acide Amide Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300276-A1 | Heterocyclic Carboxylic Acide Amide Derivatives | HCAR2, GRIN1, HCAR1 | HRH4 16/4885HRH3 39/4885ALOX15 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.