SCHEMBL4884335

SCHEMBL4884335

Oc1ccc(C=Cc2nnc(C(Cl)(Cl)Cl)o2)cc1.Oc1ccc(C=Cc2nnc(C(Cl)(Cl)Cl)o2)cc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 4/20 0.55
NQO2 P16083 3/20 0.55
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
ALOX12 P18054 3/20 0.43
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
ALOX15 P16050 2/20 0.43
THPO P40225 2/20 0.43
HIF1A Q16665 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 2/20 0.43
HPGD P15428 2/20 0.43
BLM P54132 2/20 0.43
PMP22 Q01453 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4884332 1.00 LCK (0.55) LCKNQO2MAOAMAOBALOX12
SCHEMBL167632 0.95 LCK (0.50) LCKNQO2MAOAMAOBALOX12
SCHEMBL167633 0.95 LCK (0.50) LCKNQO2MAOAMAOBALOX12
SCHEMBL126560 0.90 MAOB (0.45) LCKNQO2MAOAMAOBKDM4E
SCHEMBL126561 0.90 MAOB (0.45) LCKNQO2MAOAMAOBKDM4E
SCHEMBL321609 0.77 HPGD (0.48) MAOBKDM4EMAPTCYP3A4CYP2C9
SCHEMBL321610 0.77 HPGD (0.48) MAOBKDM4EMAPTCYP3A4CYP2C9
SCHEMBL195259 0.77 METAP2 (0.46) KDM4EMAPTCYP3A4CYP2C9HSD17B10
SCHEMBL195260 0.77 METAP2 (0.46) KDM4EMAPTCYP3A4CYP2C9HSD17B10
SCHEMBL1058172 0.76 CYP1A2 (0.48) MAOAMAOBKDM4EMAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080286685-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed