SCHEMBL126560

SCHEMBL126560

Oc1ccc(/C=C/c2nnc(C(Cl)(Cl)Cl)o2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.45
MAOA P21397 2/20 0.45
KDM4E B2RXH2 4/20 0.40
CYP1A2 P05177 4/20 0.40
CYP3A4 P08684 3/20 0.40
MAPT P10636 3/20 0.40
CYP2C9 P11712 3/20 0.40
APP P05067 6/20 0.39
HPGD P15428 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
CYP2C19 P33261 3/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126561 1.00 MAOB (0.45) MAOBMAOAKDM4ECYP1A2CYP3A4
SCHEMBL4884335 0.90 LCK (0.55) MAOBMAOAKDM4ECYP1A2CYP3A4
SCHEMBL4884332 0.90 LCK (0.55) MAOBMAOAKDM4ECYP1A2CYP3A4
SCHEMBL195260 0.85 METAP2 (0.46) KDM4ECYP1A2CYP3A4MAPTCYP2C9
SCHEMBL321609 0.85 HPGD (0.48) MAOBKDM4ECYP1A2CYP3A4MAPT
SCHEMBL321610 0.85 HPGD (0.48) MAOBKDM4ECYP1A2CYP3A4MAPT
SCHEMBL195259 0.85 METAP2 (0.46) KDM4ECYP1A2CYP3A4MAPTCYP2C9
SCHEMBL9687509 0.84 KDM4E (0.58) KDM4ECYP1A2CYP3A4MAPTCYP2C9
SCHEMBL8956565 0.84 KDM4E (0.58) KDM4ECYP1A2CYP3A4MAPTCYP2C9
SCHEMBL2739641 0.84 KDM4E (0.58) KDM4ECYP1A2CYP3A4MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
EP-2343195-B1 LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE, AND POLYMERIZABLE MONOMER FUJIFILM CORP (JP) 2014-01-29 EP disclosed
US-8426102-B2 Lithographic printing plate precursor and plate making method FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8309294-B2 2012-11-13 US disclosed
EP-2380737-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2012-10-10 EP disclosed
EP-2055476-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2012-08-01 EP disclosed
US-8221957-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8187791-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
EP-1338436-A2 Aluminum support for lithographic printing plate, method of preparing the same and presensitized plate using the same FUJI PHOTO FILM CO., LTD. (JP) 2003-08-27 EP disclosed
EP-0907107-B1 Package of photosensitive planographic printing plates FUJI PHOTO FILM CO LTD (JP) 2003-04-02 EP disclosed
US-20020094490-A1 An aluminum plate is subjected to graining, alkali etching and anodizing, a photosensitive layer becomes alkali-soluble by photothermal conversion with laser beams FUJIFILM CORPORATION (JP) 2002-07-18 US disclosed
EP-1157854-A2 Support for lithographic printing plate and presensitized plate FUJI PHOTO FILM CO., LTD. (JP) 2001-11-28 EP disclosed
EP-0671661-B1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1999-08-25 EP disclosed
EP-0907107-A2 Package of photosensitive planographic printing plates and photosensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1999-04-07 EP disclosed
EP-0684521-B1 Positive working photosensitive compositions FUJI PHOTO FILM CO LTD (JP) 1998-01-14 EP disclosed
EP-0595179-B1 Method for preparing an aluminum substrate for lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-03-19 EP disclosed
EP-0684521-A1 Positive working photosensitive compositions FUJI PHOTO FILM CO., LTD. (JP) 1995-11-29 EP disclosed
EP-0671661-A2 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed