Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.42 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702607 | 0.80 | NISCH (0.49) | NISCHESR1ESR2TTRROCK2 | |
| SCHEMBL27509560 | 0.78 | CHRNB2 (0.44) | ALOX15ADORA3ARHSD11B1AKR1C3 | |
| SCHEMBL4732107 | 0.77 | NISCH (0.44) | NISCHROCK2 | |
| SCHEMBL7531682 | 0.77 | ESR2 (0.71) | NISCHESR1ESR2TTRALOX15 | |
| SCHEMBL30615439 | 0.76 | NISCH (0.46) | NISCHESR1ESR2ROCK2 | |
| SCHEMBL13840367 | 0.76 | ALOX15 (0.56) | NISCHESR1ESR2TTRALOX15 | |
| SCHEMBL577507 | 0.75 | NISCH (0.54) | NISCHESR1ESR2TTRALOX15 | |
| SCHEMBL31264767 | 0.75 | NISCH (0.54) | NISCHESR1ESR2TTRALOX15 | |
| SCHEMBL29149123 | 0.73 | ALOX15 (0.47) | NISCHESR1ESR2TTRALOX15 | |
| SCHEMBL31290565 | 0.71 | TTR (0.68) | ESR1ESR2TTRALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432425-B2 | Isoflavonoid methylation enzyme | THE SAMUEL ROBERTS NOBLE FOUNDATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-20050150010-A1 | Isoflavonoid methylation enzyme | NOBLE RESEARCH INSTITUTE, LLC | 2005-07-07 | — | — | US | disclosed |
| US-6878859-B1 | Isoflavonoid methylation enzyme | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2005-04-12 | — | — | US | disclosed |
| EP-1183376-A1 | ISOFLAVONOID METHYLATION ENZYME | The Samuel Roberts Noble Foundation, Inc. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071736-A1 | ISOFLAVONOID METHYLATION ENZYME | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2000-11-30 | — | — | WO | disclosed |