Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894734 | 0.96 | P2RX7 (0.92) | P2RX7 | |
| SCHEMBL14113745 | 0.88 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL4894824 | 0.87 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL4893872 | 0.84 | P2RX7 (0.83) | P2RX7 | |
| SCHEMBL14113744 | 0.83 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL4895473 | 0.83 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL4895016 | 0.82 | P2RX7 (0.91) | P2RX7 | |
| SCHEMBL4895624 | 0.80 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL4884487 | 0.80 | P2RX7 (0.81) | P2RX7 | |
| SCHEMBL4896756 | 0.80 | P2RX7 (0.75) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182874-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2008-07-31 | — | — | US | claimed |
| US-20080182874-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182874-A1 | Novel Compounds | REN, F12, GPR119 | P2RX7 1672/4885HSD11B1 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.