Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 7/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752244 | 0.90 | PGR (0.39) | PGRSLC22A12KDRAR | |
| SCHEMBL14021725 | 0.88 | PGR (0.39) | PGRSLC22A12KDRAR | |
| SCHEMBL4978023 | 0.88 | PGR (0.45) | PGRSLC22A12AR | |
| SCHEMBL4748816 | 0.86 | PGR (0.36) | PGRSLC22A12KDRAR | |
| SCHEMBL4947332 | 0.85 | PGR (0.38) | PGRSLC22A12KDRARTRPV4 | |
| SCHEMBL4748870 | 0.84 | PGR (0.40) | PGRSLC22A12KDRAR | |
| SCHEMBL14022511 | 0.83 | ALOX5AP (0.31) | PGR | |
| SCHEMBL4748819 | 0.81 | PGR (0.37) | PGR | |
| SCHEMBL4884834 | 0.78 | PGR (0.36) | PGRSLC22A12KDR | |
| SCHEMBL4607965 | 0.78 | PGR (0.42) | PGRSLC22A12KDRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |