Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.57 |
| ▸ | PGR | P06401 | 4/20 | 0.57 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | PARP1 | P09874 | 7/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331760 | 0.85 | NR3C1 (0.74) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL331702 | 0.78 | NR3C1 (0.64) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL331489 | 0.77 | NR3C1 (0.78) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL3245440 | 0.77 | NR3C1 (0.62) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL331677 | 0.76 | NR3C1 (0.71) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL12893478 | 0.76 | NR3C1 (0.58) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL12893477 | 0.76 | NR3C1 (0.58) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL12893402 | 0.76 | NR3C1 (0.63) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL12893403 | 0.76 | NR3C1 (0.63) | NR3C1PGRARPARP1TRPV1 | |
| SCHEMBL3537084 | 0.76 | NR3C1 (0.82) | NR3C1PGRARPARP1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153859-A1 | MULTIPLY-SUBSTITUTED TETRAHYDRONAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | REHWINKEL HARTMUT | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153859-A1 | MULTIPLY-SUBSTITUTED TETRAHYDRONAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | DHPS, TNF, IL1B | NR3C1 1062/4885PGR 3101/4885AR 3491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.