SCHEMBL4885018

SCHEMBL4885018

CCC(CO)CCCC(O)C(C)CC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
LMNA P02545 3/20 0.40
CYP2D6 P10635 2/20 0.34
SPHK1 Q9NYA1 2/20 0.34
CYP3A4 P08684 2/20 0.34
GMNN O75496 1/20 0.34
POLB P06746 1/20 0.34
THPO P40225 1/20 0.34
MTOR P42345 1/20 0.34
BLM P54132 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
MAPT P10636 1/20 0.34
CETP P11597 1/20 0.34
HTT P42858 1/20 0.34
UBE2N P61088 1/20 0.34
TRPA1 O75762 2/20 0.32
TRPV1 Q8NER1 1/20 0.32
TDP1 Q9NUW8 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14698566 0.81 ALDH1A1 (0.58) ALDH1A1LMNACYP2D6SPHK1CYP3A4
SCHEMBL11310510 0.81 ALDH1A1 (0.58) ALDH1A1LMNACYP2D6SPHK1CYP3A4
SCHEMBL6651648 0.78 TSHR (0.43) LMNACYP2D6SPHK1CYP3A4GMNN
SCHEMBL5907121 0.78 PTPN1 (0.41) ALDH1A1LMNACYP2D6SPHK1CYP3A4
SCHEMBL107336 0.78 LMNA (0.42) LMNACYP2D6SPHK1CYP3A4GMNN
SCHEMBL30987409 0.77 TRPV1 (0.52) LMNACYP2D6SPHK1CYP3A4GMNN
SCHEMBL4892117 0.77 ALDH1A1 (0.79) ALDH1A1LMNACYP2D6SPHK1CYP3A4
Isopropyl Alcohol SCHEMBL5888587 0.76 ALDH1A1 (0.86) ALDH1A1LMNACYP2D6SPHK1CYP3A4
SCHEMBL7753996 0.76 TRPV1 (0.36) SPHK1TRPA1TRPV1TSHR
SCHEMBL1425272 0.76 ALDH1A1 (0.50) ALDH1A1LMNACYP2D6SPHK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080293880-A1 Liquid, Thermally Curable Mixtures, Their Preparation and Use BASF COATINGS AG (DE) 2008-11-27 US claimed