Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123336 | 0.96 | CA4 (0.36) | CA1CA4FAHD1 | |
| SCHEMBL3802480 | 0.96 | CA4 (0.36) | CA1CA4FAHD1 | |
| Water SCHEMBL9156407 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 | |
| Water SCHEMBL7936916 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 | |
| SCHEMBL7174619 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 | |
| SCHEMBL2004086 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 | |
| SCHEMBL1778898 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 | |
| Water SCHEMBL9160101 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 | |
| Zinc Ion SCHEMBL673444 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 | |
| SCHEMBL251495 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7364792-B2 | Spun-dyed polyurethaneurea fibres, a process for their production and their use for producing fabrics | DORLASTAN FIBERS GMBH (DE) | 2008-04-29 | — | — | US | disclosed |
| US-20060210794-A1 | Spun-dyed polyurethaneurea fibres, a process for their production and their use for producing fabrics | DORLASTAN FIBERS GMBH | 2006-09-21 | — | — | US | disclosed |
| EP-1431429-A1 | Process for the production of polyurethane-urea fibres containing a combination of polydimethylsiloxanes, alkoxylated polydimethylsiloxanes and fatty acid salts | Bayer Faser GmbH (DE) | 2004-06-23 | — | — | EP | disclosed |